Alice Marshall, the daughter of William Marshall, a railway engineer, was born in Derby on 27th January, 1866. After leaving school she worked as a domestic servant.
In 1886 Alice married William Wheeldon, a widowed engine fitter some fourteen years her senior, at the Register office in West Derby. The couple moved to 87 Marsh Lane, Bootle. Over the next few years Alice Wheeldon gave birth to Nellie (1888), Hettie (1891), William (1892) and Winnie (1893).
In 1901 Alice and her family moved to 91 Stanhope Street, Derby. William Wheeldon was now working as a commercial traveller whereas Alice Wheeldon ran a second-hand clothes shop at 12 Pear Tree Road. The Derby & District Directory records that she bought and sold the contents of people's wardrobes.
Alice Wheeldon became active in politics. She was a socialist and a member of the Socialist Labour Party (SLP) . She was also active in the Women's Social and Political Union (WSPU). Her daughters, Hettie Wheeldon and Winnie Wheeldon, shared her feminist political views.
The outbreak of the First World War caused conflict between Alice and the WSPU. Alice was a pacifist and disagreed with the WSPU's strong support for the war. Sylvia Pankhurst and Charlotte Despard established the Women's Peace Army, an organisation that demanded a negotiated peace. Alice, Hettie Wheeldon and Winnie Wheeldon, all joined this new political group. Other members included Helena Swanwick and Olive Schreiner.
Alice and her daughters also joined the No-Conscription Fellowship (NCF).